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In a small, exploratory, randomized, placebo-controlled trial that included 27 cancer patients being treated with a chemotherapy agent known to cause ototoxicity, those given oral D-methionine (100 mg per kg of bodyweight) along with chemotherapy were protected from drug-induced hearing loss

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Khandaker** GM, Pearson RM, Zammit S, Lewis G, Jones PB (2014)