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developed SIMS imaging to explore the uptake and subcellular localization of iron in alveolar macrophages, providing discernment and therapeutic strategies on iron metabolism at the subcellular level to reduce the cytotoxicity of iron overload [228]

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In addition, the host metabolic profile was disturbed after HFD treatment and improved after GPS treatment

At the genetic epidemiology level, Mendelian randomization-based analyses provide support for causal relationship hypotheses, though evidence strength remains preliminary (155)

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimers disease markers in subjects with mild cognitive impairment