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Skin health, redefined

Iglesias et al., 2014)

(Wilson and Nicholson, 2017)

While the precise etiology remains incompletely understood, central obesity and insulin resistance (IR) stand prominently as pivotal contributors to MetS onset

In the rodent studies reported to date it has generally been described as tolerated across the dose ranges examined, but comprehensive controlled human safety data do not exist, so conclusions about tolerability in people remain unconfirmed