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Inflammation is initiated through the activation of Pattern Recognition Receptors (PRRs), such as plasma membrane-expressing Toll-like Receptors (TLRs) and cytosolic-expressing NOD-like Receptors (NLRs), in response to the detection of exogenous Pathogen-Associated Molecular Patterns (PAMPs)

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Landau SM, Fero A, Baker SL, Koeppe R, Mintun M, Chen K, et al

Therefore, whether the Warburg effect induces the development of PAH through lactylation still needs further verification [230]