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Description

Sofic E, Lange KW, Jellinger K, Riederer P

Trial candidates are generally adults with type 2 diabetes and a BMI over 30 who have not achieved adequate glucose or weight control with standard therapies like metformin or a single GLP-1 agonist

This connects by showing how withdrawal symptoms and duration differ across opioid types

It is generally observed after protracted exposure but also after acute treatment (acute tolerance) and it is not observed for all the pharmacological effects