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Severe PS may present with decreased cardiac output symptoms such as exertional dyspnea and subsequently symptoms of congestive cardiac failure

[Abstract]2025 Nov 7;11(1):511

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Behaviorally, the LAC treatment during the last part of chronic restraint stress (CRS) enhanced resilience and reversed the effect of CRS, which is shown by increased social interaction and reduced passive behavior in a forced swim test ( Disorders of metabotropic glutamate (mGlu) receptors and neurotrophins have significant negative effects on neuroplasticity, leading to depression, but LAC regulate brain type 2 metabotropic glutamate (mGlu2) receptors and N-methyl-D-aspartic acid (NMDA) receptors to induce antidepressant effect ( Neurotrophic factors are associated with the pathogenesis of depression (98), but there is still a lack of relevant research on the effect of LAC on VEGF in mental illness

Gholami SS and Lue TF: Correction of penile curvature using the 16-dot plication technique: a review of 132 patients