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Studies showed CJC-1295 DAC increased mean GH plasma levels by 2-10 fold and IGF-1 levels by 1.5-3 fold sustained over multiple weeks with weekly dosing

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This activation may occur due to regeneration and reparation processes as well as mitochondrial biogenesis ( Looking more closely at the effect of the ex vivo stimulus, LPS stimulation resulted in a lower OCR compared to unstimulated cells for basal respiration, ATP production, and maximal respiration