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337,338 It has been shown to prevent the progression of age-dependent intervertebral disc degeneration, 339 reduce intestinal SnCs and excessive inflammation in aged mice, 340 and effectively induce apoptosis, thereby eliminating SnCs and the SASP burden in adipose tissue

Ethics statement The studies involving human participants were reviewed and approved by This research was approved by the Institutional Review Board (IRB

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However, excessive or sustained inflammation results in the destruction of tissues, followed by the development of inflammatory diseases

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