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Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins

Glutatin y parkinson Varios estudios han demostrado una deficiencia en glutatin reducido (GSH) en la sustancia nigra de pacientes con enfermedad de Parkinson (EP)

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

Using chemical inhibitor and KO mice, c-Jun amino-terminal kinase 2 (JNK2) was demonstrated to play a major role in morphine- but not fentanyl-induced G protein uncoupling (Melief et al., 2010)

Ketones and lactate increase cancer cell stemness, driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics