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Here, we reported an interdisciplinary study of AKAP11 neuronal function and the consequence of the loss-of-function in AKAP11 in both genetic mouse models and human pluripotent stem cell (PSC)-induced neurons (iNeurons) by integrating multi-omics, cell biology, and electrophysiology approaches

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Our investigation addresses the fundamental basis of a popular approach in coatomer-client structural biology, in using WD40 as a substitute for WD40 for client tail peptide co-crystallization

Tanshinone (TAN) and -mangostin (MAN), drugs known in southern Asia used in ancient pharmacopoeia has proven its cytotoxicity against various cancer cell lines