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Using a modified form of thiol-ene chemistry and readily available materials, we demonstrate a simple, one-step method for creating gel homogenates and beads with affinity toward GST tagged proteins

NaBPC157 completely prevented sudden decrease in heart rate and conduction disturbances induced by desipramin (PQ prolongation and QRS widening)

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At transcriptional level, EGFR deletion significantly reduced expression of SREBF1 (a major transcriptional regulator of fatty acid synthesis) along with its downstream fatty acid synthase gene and increased expression of lipolysis genes such as PNPLA2