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NF-Bdependent lymphoid enhancer co-option promotes renal carcinoma metastasis

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Mdr2-/- mice resulted in markedly reduced tumor number and size by ~50% compared to control group

Each follicle moves through several phases: Anagen: The active growth phase Catagen: A short transition phase Telogen: The resting phase Exogen: The phase when the strand sheds Hair thinning can occur when follicles spend less time in anagen, enter telogen too early, or gradually produce shorter and finer strands