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Mol Cancer Ther 2020 Feb;19(2):397-408 44

However, maternal ageing is accompanied by a precipitous decline in oocyte quality

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Clinical observations found that HCC patients with higher baseline gut flora -diversity respond better to ICI therapy, and classifiers based on serum metabolites perform excellently in predicting potential beneficiaries of immunotherapy, providing a basis for patient stratification via microbial features before treatment