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Peptide signaling increases cellular activity, and jumping straight to high concentrations can overwhelm cells that aren't accustomed to that level of stimulation

These cardiovascular effects suggest potential applications in ischemic heart disease, peripheral vascular disease, and vascular injury, though clinical translation requires confirmation of effects in human subjects

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(2005) Diagnostic value of quantitative hepatic copper determination in patients with Wilson's disease

Research has confirmed that the peptide lacks the systemic effects of growth hormone, showing no impact on IGF-1 levels, glucose metabolism, or growth-promoting effects in other tissues