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There are no validated outcome measures of RBC efficacy that assess tissue oxygenation function

In a multicenter PPMI cohort, free water in the posterior region of the SN increased in de novo PD from baseline to 1, 2, and 4 years, and changes in free water within 1 year predicted changes in the Hoehn & Yahr scale at 4 years (Burciu et al., 2017)

[DOI] [PubMed] [Google Scholar] Dell'Aglio E., Giustini C., Kraut A., Cout Y., Costa A., Decros G., Gibon Y., Mazars C., Matringe M., Finazzi G., Curien G