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One hundred and three metabolites had significant negative associations with increased N -formylmethionine abundance, primarily by decreased lysophosphatidylcholines (See Additional file 9: Highlights and Additional file 4: Days 0, 3, and 7 VITdAL-ICU tab for full data)

However, active lipid metabolism occurs in lung tissues, especially within the alveolar area, where surfactant homeostasis is exquisitely regulated to ensure continuous optimal function in each respiration cycle

107 Hyperglycemia also disrupts the structure and function of the bloodbrain barrier (BBB) by inducing oxidative stress and secondary inflammatory responses, impairing brain function and the biosynthesis of neurotransmitters

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