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Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors

1995;118 Suppl:S4350

A switch from L-peptides to DRI peptides will not change this scenario for the S-shaped A 42 fibrils, however, it will still lead to a smaller number of hydrogen bonds in the DRI-fibril than seen in the L-fibril

After two rounds of evolution, we identified two biosensors that were highly selective for S -THP (STHP2) or R -THP (RTHP2), showing a 51-fold or 16-fold difference in EC 50 between the enantiomers, respectively (Fig