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In the case of HCT-116 and Caco-2 cells, IC 50 values for all compounds exceeded 200 M

I get asked about these every single week in clinic

[26] identified elevated plasma neurofilament light chain (NfL) levels in ME/CFS patients, which was correlated with cognitive deficit and autonomic dysfunction, thus implicating NfL as a promising biomarker for neuroaxonal damage and associated neurological dysfunction in ME/CFS

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Yes, but it is always best to consult with a healthcare provider before combining supplements