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doi: 10.3389/fimmu.2025.1701505 Received 08 September 2025 Revised 24 November 2025 Accepted 25 November 2025 Published 09 December 2025 Volume 16 - 2025 Edited by Qinglei Hang, Yangzhou University, China Reviewed by Saptak Banerjee, Chittaranjan National Cancer Institute (CNCI), India Bingbing Zhang, Heilongjiang Bayi Agricultural University, China Updates Copyright 2025 Liu, Tang, Huang, Tang and Yang

This publication resulted from the data collected using the beamtime obtained through NECAT BAG proposal # 311950

Swiss Acad

For complete removal of the proteolytic enzyme, organoids were washed twice with an excessive volume of DMEM/F12 medium before re-entry into PureCol EZ Gel