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Initially, injections may be given weekly or biweekly until levels improve, followed by maintenance doses every 1-3 months

But injections of hyaluronic acid might also be indicated in individuals with: Intolerance or contraindications to nonsteroidal anti-inflammatory drugs (NSAIDS) Patients who are poor surgical candidates Chondrocalcinosis Any type of cartilage injury Clinical evidence shows support for using intra-articular hyaluronic acid in individuals intolerant to NSAIDS and those wishing to defer or not willing to undergo surgery

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doi:10.1093/jn/134.6.1558S

Nevertheless, it is crucial to underscore that the content of this manuscript has been sourced exclusively from scientific peer-reviewed data