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Folic acid: Ingesting amounts greater than the Tolerable Upper Intake Level may mask vitamin B12 deficiency symptoms (33)

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Moreover, the hyperhomocysteinemia associated with an increased cardiovascular risk is stronger in non-insulin-dependent diabetes mellitus than in normal subjects (Hoogeveen et al, 1998)

Even if Intrinsic Factor is lacking, the sheer concentration of the liquid forces approximately 1-2% of the dose directly into the bloodstream, ensuring adequate delivery to the tissues