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Immunohistochemical studies indicate that cGMP levels is not fiber type specific and that cGMP is found near the subsarcolemma and in close proximity to NOS1 (291)

Its main role in the body is as the central driver of the stress hormone system, known as the hypothalamicpituitaryadrenal axis

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RNA-Seq Total RNA from three samples from each group (MOD, SEV and CTRL) at endpoints A and B (total 18 samples) was used to construct cDNA libraries with the TruSeq Stranded mRNA kit (Illumina, San Diego, CA) and the indexed fragments were sequenced on the NGS NextSeq 500 (Illumina) with the NextSeq 500/550 High Output 2x75 cycles kit (Illumina)