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Zoccali, C

Nature 2018, 562 (7728), 519

New surgical and stimulation approaches are reshaping the sector, and technology improvements may enhance possible outcomes

In the same way, the depletion of LRRK2 or application of LRRK2 inhibitors decreases ROS, restores mitochondrial function, prevents mitochondrial fragmentation, and blocks increases in proapoptotic proteins including caspase 3, Bax, and apoptotic-inducing factor [53,54,55]