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RXR agonists are also effective in the treatment of some neuropathies, such as Alzheimers disease 61 and Parkinsons disease in animal models 62

Moreover, SARS-CoV-2 degrades checkpoint kinase (CHK)1 (190), an effector downstream to Ataxia telangiectasia and Rad3 related protein (ATR) that earlier had been demonstrated to be induced in SARS-CoV-2-infected Vero-6 cells (284)

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In general, the estimates generated by the new model are comparable to those generated under the original model

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