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"Given their side effects, we assume that they are steroids," she told AFP, adding that prolonged use in high doses can cause depigmentation, diabetes and hypertension

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Increased expression of tight junction proteins was a mechanism by which progesterone and estrogen facilitated wound healing and epithelial barrier function in intestinal epithelial cells, as reported using 2D cell lines and IBD patient-derived inflammatory organoid models (252)

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Pechyen, C., Ponsanti, K., Tangnorawich, B