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(2003) first reported that stimulation of the hippocampal CA1 region resulted in a noticeable increase in the activity of Rho GTPases

10.1007/s000180050041 24 DavletovaS.RizhskyL.LiangH.ShengqiangZ.OliverD

By secreting Il-1, TNF and complement component subunit 1q, the activated microglia induce the formation of neurotoxic reactive astrocytes which lose the ability to support neuronal survival, outgrowth, synaptogenesis and phagocytosis, leading to the death of neurons and oligodendrocytes (Zhang L

Of particular interest is that NK-lysin fragments and derivates also show potent antimicrobial activities by concurrent optimization of peptide stability and minimized cytotoxicity