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Cyclosporine A was the most frequently used immunosuppressant agent (384 patients, 18 studies), providing an ORR of 74% (95% CI, 66-82) with a similar ORR in first- (73%) and second-line (76%) treatment and when cyclosporin was used as monotherapy (83%) or with corticosteroids (77%)

2020;15(11):e0240689

Previous studies suggested that the levels of palmitic and oleic acid were significantly increased in the plasma of MS-affected subjects compared with those in controls (118), consistent with our results