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Genes & Dis 10(4):13671401 Andreyev J, Ross P, Donnellan C, Lennan E, Leonard P, Waters C et al (2014) Guidance on the management of diarrhoea during cancer chemotherapy

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In the oligodendrocyte lineage, CNS-specific inactivation of the Nbn gene, which encodes NBS1, leads to hypomyelination via oligodendrocyte apoptosis and a lack of OPC differentiation by dysregulation of transcription regulators (HDACs, MYRF, etc.) [191, 192]