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[64] demonstrated the ternary complex X-ray crystal structures of NNMT in bound form with MNA, which indicates that MNA can bind to the active site of NNMT, thereby inhibiting NA binding and inhibiting the activities of NNMT

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What we can say with confidence is that the compounds target non-overlapping pathways, show no receptor competition in pharmacological models, and have individual safety profiles that don't predict catastrophic interaction

2020 Oct-Dec;15(4):365-369