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El-Banna et al

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This method comprises contacting a cell with a ferroptosis modulator, which comprises a compound having the structure selected from the group consisting of: and combinations thereof, or an N-oxide, crystalline form, hydrate, or a pharmaceutically acceptable salt thereof

n p , Representative histograms and quantification of caspase-3 activation ( n , n = 3), PS externalization ( o , n = 3) and NETs formation ( p , n = 8) in WT and XKR8 KO neutrophils treated with PMA (100 nM), with or without Apocynin (30 M), DPI (10 M) or NA-11 (1 M)