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Copper-mediated neurotoxicity and genetic vulnerability in the background of neurodegenerative diseases in C

First, for each metabolite in this set, the feasible flux range of its exchange reaction was computed via FVA

Synonyms GSH-PX Sample Type Serum, plasma, cells, cell culture supernatant, tissue Sensitivity 17.17 U Detection Range 17.17-518.32 U Detection Method Colorimetric method Assay type Enzyme Activity Assay time 40 min Precision Average inter-assay CV: 6.200% | Average intra-assay CV: 2.400% Other instruments required Micropipettor, Incubator, Vortex mixer, Centrifuge Other reagents required Normal saline (0.9% NaCl), PBS (0.01 M, pH 7.4) Storage 2-8 Valid period 12 months

As expected, Dox caused a notable reduction in the overall number of pups born during the breeding trial (Fig

In Handbook of Clinical Neurology, Vol