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10.1038/sj.ejcn.1601685 117 RajagukgukY

Phytocannabinoids proved to reverse the alterations observed in the ECS, including changes in cannabinoid receptor expression and dysregulation of endocannabinoid signaling due to Parkinsonism

Central regulators of this pathway include the Bcl-2 family of proteins, which orchestrate mitochondrial membrane integrity, and the caspase family of proteases, which execute the death program