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A community-driven global reconstruction of human metabolism

doi: 10.1002/kin.20082 17 GarzonD.ArizaA.RegazzoniL.ClericiR.AltomareA.SirtoriF

Since we observed an activation of NRF2 upon GSH depletion, we expected NRF2 to be essential for preventing liver damage

High expression of GT provides cells with greater quantities of cysteine through the breakdown of extracellular GSH (Gerber and Thung, 1980

Stool sample analysis for general HBM studies is typically not conducted, in part because it does not necessarily provide a marker of systemic bioavailability