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[17] The ratio of reduced glutathione to oxidized glutathione within cells is a measure of cellular oxidative stress [18] [11] where increased GSSG-to-GSH ratio is indicative of greater oxidative stress

Said hyperbranched dendritic moieties contain a number of permanent linkages to either spacer moieties connected to a backbone moiety and on the other side connected to a crosslinking moiety (asterisk) or to spacer moieties (white rectangle) which are connected to transient prodrug linkers (black arrow)

van Haaften G, Dalgliesh GL, Davies H, et al

2022 Apr 1;105(4):397-405

Again, further studies would be needed to examine the synergy with traditional therapies used in AD, as synergistic effects between some antibiotic therapies and vitamin E derivatives involved in various infections are already known (126, 127)