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usually mild) Fishy body odor (due to trimethylamine production) Headache (occasional) Increased appetite (some patients) When to Contact Healthcare Provider: Severe GI symptoms Signs of allergic reaction (rash, swelling) Increased seizure frequency (if history of epilepsy) Unusual bleeding or bruising (if on warfarin) Symptoms of hypothyroidism (fatigue, weight gain, cold intolerance) Drug and Supplement Interactions: Warfarin: May increase anticoagulant effect

Cureus 11 (12), e6404

doi:10.1007/s12052-012-0439-5

Moreover, eHSP90 might mediate the tumor-retention effect of CHAMPs, as it facilitates cellular uptake by binding to CHAMPs

192 Excessive NETs have also been implicated in delaying diabetic wound healing by promoting endothelial-to-mesenchymal transition through the Hippo pathway