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Description

Sun Y, Drevets W, Turecki G, Li QS

2017;62:e12393

Darkcomplexioned individuals, including black, Asian, and Latino people, frequently show patchy to generalized hyperpigmentation of the oral mucosal tissues

As the transporter-utilizing (pro)drugs and nanocarriers are distributed in and out of the brain parenchymal cells via transporters expressed at cellular membranes, the ISF concentration of the unbound (pro)drug or nanocarriers is not necessarily equal to that in the brain parenchymal cells (49)