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Evaluation of the protective effects of chlorogenic acid (caffeoyl quinic acid) found in coffee on endothelial function in aortic rings isolated from C57BL mice and human aortic endothelial cells (HAECs) under oxidative stress revealed increased NO production and HO-1 expression (Jiang et al., 2016)

Another example using the YTE modification is nirsevimab, a mAb targeting the RSV fusion (F) glycoprotein developed by AstraZeneca and Sanofi Pasteur 85 (see below)

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3.8 Principal component analysis (PCA)-based free energy landscape (FEL) of proteinligand complexes We analyzed the collective motion captured by the first two principal components (PCs) and plotted 2D projections for PC1 and PC2 (Figures 10A, B)