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The reduced form of GSH helps detoxify reactive, toxic metabolites of CCl 4 [5]

While each antioxidant has its specific mechanism of action, they all function to protect cells from oxidative stress, which can lead to cancer

In oxalate-stimulated HK-2 cells, iron levels increase, accompanied by the upregulation of ACSL4 and TFR1 expression and the downregulation of GPX4, SLC7A11, and ferritin light chain expression, along with typical ferroptosis-related mitochondrial alterations (275)