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Metabolic pathway enrichment analysis revealed that CAR T cell products of LTR have significantly increased pools of TCA metabolites, nucleotide biosynthesis intermediates, sphingolipid metabolism, and intermediates in central energy metabolism, as well as significantly decreased nucleotide catabolic and tRNA metabolism intermediates, which is critical for T cell activation 10 , compared to those of STR (Fig

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doi: 10.3389/fphar.2023.1217306 Received 05 May 2023 Accepted 06 July 2023 Published 17 July 2023 Volume 14 - 2023 Edited by Irfan A