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The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed

According to the National Institutes of Health, 3 out of 4 people suffering from an opioid use disorder have sleep problems

Ishikawa H, Imano M, Shiraishi O, Yasuda A, Peng Y-F, Shinkai M, et al

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However, a healthy diet should include a number of items that boost collagen production