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This is due to several factors that differ between the controlled conditions of in vitro studies and the complex biological processes in living organisms, including interactions between different cell types, organ systems, and environmental variables (e.g., gut microbiota or circulation) that can influence how a drug works

Diagnostic features: A moderate compression of the surrounding tissues is usually seen

While axon-positive labeling was sparse in distal stumps, we cannot rule out minor contributions of spontaneously regenerating axons to ultrasound signatures

The main limitation is that reduced GSH is vulnerable to stomach acid and digestive enzymes, which break it down before absorption