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This is an important task in light of the ever-growing prevalence of this disorder while no effective pharmacological treatment has been found so far

Eur J Biochem 1984;138:491-5

Yi, R., Li, Y.R

In laboratory and pre-clinical settings, DSIP has been studied as a uniquely multifunctional endogenous regulatory neuropeptide across sleep, stress, neuroendocrine, neuroprotection, and geroprotective research applications: Sleep biology delta-wave SWS promotion, sleep homeostasis modulation, sleep efficiency and sleep latency research Sleep EEG research delta-wave induction, SWS vs REM sleep architecture, and sleep stage analysis via polysomnography Sleep neuromodulator pharmacology DSIP vs sedatives and hypnotics

Lipid droplets accumulate near mitochondria, forming membrane contact sites that provide lipid substrates for autophagic membrane expansion and help maintain lysosomal homeostasis [225]