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48 Stressors, such as dehydration, fever and infection can lead to a functional decline and neurodegenerative regression in individuals with MD

Besides its role in energy metabolism, a number of studies have shown that C2 actions range from antioxidant, neuromodulatory, and neuroprotective effects to modulation of gene expression [19,20,21,22]

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Thirty-two participants completed Phase I, of whom 29 (90.6%) were classified as high-TMAO producers ( 5 mol/L and 50% increase from baseline to 24-h follow-up)