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BACH1 inhibition stimulates NRF2 signaling and induces antioxidant genes expression, which inhibits the occurrence of cellular senescence under oxidative stress, and thus prevents mitochondrial ROS production

R.MikhalkovaD.BoleI.LeibowitzJ

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Mucus secretion includes bicarbonate, which helps maintain a neutral pH at the epithelial surface, while surfactant phospholipids serve as a physical barrier alongside luminal digestive enzymes [6]

Amination potentially augments the ameliorative effect of curcumin on inhibition of the IL-6/Stat3/c-Myc pathway and gut microbial modulation in colitis-associated tumorigenesis