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Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase)

Nat Rev Neurol 20 , 695707 (2024)

Bcl-2, B-cell CLL/lymphoma 2

The multifaceted status of DRE patients underscores the emphasis on non-pharmacological options, and therapies that target multiple mechanisms are likely to be more effective to treat DRE ( Clinical studies show that both modalities (VNS and KD) lead to a seizure frequency reduction (SFR) by at least 50% in half of the DRE patients