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MOTS-c is a mitochondria-derived peptide commonly discussed in research contexts around metabolic signalling, energy regulation, exercise response, and cellular resilience

The current review sought to summarize the recent findings on how activated ATFs regulate macrophage development, survival, migration, phagocytosis, activation, cytokine secretion, polarization and their involvement in immune, metabolic, cardiovascular, neurological disorders and cancer, with a particular emphasis on their therapeutic potential (Fig

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