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Progressive liver fibrosis also enhances HSC and portal fibroblast activation through matrix rigidity, creating a positive feedback loop of fibrogenesis and oncogenesis (154)

Hypothalamic dysfunction, both pre- and post-treatment, can lead to obesity, sleep disorders, and cognitive impairment

[DOI] [Google Scholar] 57.Serna-Escolano V., Gimnez M.J., Castillo S., Valverde J.M., Martnez-Romero D., Guilln F., Serrano M., Valero D., Zapata P.J

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Erythrocytes lack gamma-glutamyl transpeptidase and this enzyme activity also varies in other tissues