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This places it in the same category as many research peptides, available through certain channels but without official sanction for human use

The details on the GSM model comparison for all the generated models is available in Supplementary Data 1

Notably, GSH is the most important non-enzymatic antioxidant in animals, whereas creatine helps to store ATP in the form of phosphocreatine for physiological processes such as muscle contractions, protein synthesis, and nutrient transport

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For example, in a murine model exposed to chronic hypoxia (10% O 2 ), the conditional deletion of HIF-2 in vascular cells (Wt1 lineage) resulted in cardiomegaly, ventricular hypertrophy, dilation, and systolic dysfunction, indicating that vascular signaling mediated by HIF-2 contributes to preserving cardiac homeostasis under chronic hypoxia [93]