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These extremely rare side effects include: Reactive thrombocytosis during the first week of use in megaloblastic anaemia Hypersensitivity reactions including: rash, itching, exanthema, antibodies to HYDR0XOCOBALAMIN-transcobalamin II Anaphylaxis Hypokalaemia Headache, paraesthesia, tremor Irregular heartbeat (arrhythmias secondary to hypokalaemia) Nausea Vomiting Diarrhoea Fever, chills, hot flushes, dizziness, malaise, pain and / or swelling at the injection site Acne Abnormal colouration of the urine (chromaturia) B12 injections work quickly

Patients who stop at eight weeks because they are not seeing dramatic scan results are stopping right before the payoff phase

It can be a serious problem and will need a GP to diagnose and recommend treatment

Shari Forschen is a Registered Nurse at Sanford Health in North Dakota

B12 deficiency has been associated with fatigue, low mood, and poor circulation , which can contribute to decreased sexual interest or performance