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injections with tesaglitazar (2 mg/kg body weight/day) or a combination of tesaglitazar and resveratrol (100 mg/kg body weight/day) for 7 days (Figure 7A)

Upon completion of the deep sleep phase, the cycle transitions to REM sleep, marked by heightened brain activity and dreaming

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Ligand-induced phosphorylation of the RTKs induces recruitment of the regulatory subunit of PI3K (p85) to the RTKs, relieving the inhibitory interaction with the catalytic subunit (p110) and resulting in activation